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Transcription profiling of neurons or astrocytes treated with grape seed extract


ABSTRACT: We examined the effect of grape seed extract (GSE), which are known to protect neurons against oxidative stress, on primary cultures of hippocampal astrocytes. GSE increased interleukin-6 (IL-6) expression. Microarrays are used to examine the effects of GSE on primary cultures of hippocampal neurons and astrocytes. Experiment Overall Design: Primary cultures of hippocampal neurons were treated with 0, 1, or 10 ug/ml of GSE for 24 hrs. Primary cultures of hippocampal astrocytes were treated with 0, 1, 10, or 100 ug/ml of GSE for 24 hrs.

ORGANISM(S): Rattus norvegicus

SUBMITTER: Shihori Tanabe 

PROVIDER: E-GEOD-15285 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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