Chronic Hypoxia predicts Poor Prognosis in Hepatocellular Carcinoma
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Joke Allemeersch
PROVIDER: E-GEOD-15366 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
A seven-gene set associated with chronic hypoxia of prognostic importance in hepatocellular carcinoma.
van Malenstein Hannah H Gevaert Olivier O Libbrecht Louis L Daemen Anneleen A Allemeersch Joke J Nevens Frederik F Van Cutsem Eric E Cassiman David D De Moor Bart B Verslype Chris C van Pelt Jos J
Clinical cancer research : an official journal of the American Association for Cancer Research 20100630 16
<h4>Purpose</h4>Hepatocellular carcinomas (HCC) have an unpredictable clinical course, and molecular classification could provide better insights into prognosis and patient-directed therapy. We hypothesized that in HCC, certain microenvironmental regions exist with a characteristic gene expression related to chronic hypoxia which would induce aggressive behavior.<h4>Experimental design</h4>We determined the gene expression pattern for human HepG2 liver cells under chronic hypoxia by microarray a ...[more]
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2008-10-25 | E-GEOD-8343 | biostudies-arrayexpress
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2010-05-07 | E-GEOD-15901 | biostudies-arrayexpress
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2015-03-02 | E-MTAB-1207 | biostudies-arrayexpress
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2010-08-28 | E-GEOD-17756 | biostudies-arrayexpress