Unknown,Transcriptomics,Genomics,Proteomics

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NFAT-mediated gene expression response to LPS in murine dendritic cells and macrophages


ABSTRACT: This SuperSeries is composed of the following subset Series: GSE15718: Gene expression in dendritic cells stimulated with LPS in conditions allowing or inhibiting NFAT activation GSE15720: Apoptosis genes specifically modulated by NFAT in LPS-activated dendritic cells GSE15721: Gene expression in macropages stimulated with LPS in conditions allowing or inhibiting NFAT activation Refer to individual Series

ORGANISM(S): Mus musculus

SUBMITTER: Francesca Granucci 

PROVIDER: E-GEOD-15759 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications


Toll-like receptors (TLRs) are the best characterized pattern recognition receptors. Individual TLRs recruit diverse combinations of adaptor proteins, triggering signal transduction pathways and leading to the activation of various transcription factors, including nuclear factor kappaB, activation protein 1 and interferon regulatory factors. Interleukin-2 is one of the molecules produced by mouse dendritic cells after stimulation by different pattern recognition receptor agonists. By analogy wit  ...[more]

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