Unknown,Transcriptomics,Genomics,Proteomics

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MicroRNA expression patterns in mouse tissues and staged embryos


ABSTRACT: RNA from seven adult mouse tissues, four staged whole mouse embryos, ES cells, 3 day and 28 day embryoid bodies was profiled against the microRNA microarray. A custom microarray platform for analysis of microRNA gene expression; Nature Methods 1, 47 - 53 (2004) Keywords = microRNA Keywords = miRNA Keywords: other

ORGANISM(S): Mus musculus

SUBMITTER: Charles Perou 

PROVIDER: E-GEOD-1635 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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A custom microarray platform for analysis of microRNA gene expression.

Thomson J Michael JM   Parker Joel J   Perou Charles M CM   Hammond Scott M SM  

Nature methods 20040929 1


MicroRNAs are short, noncoding RNA transcripts that post-transcriptionally regulate gene expression. Several hundred microRNA genes have been identified in Caenorhabditis elegans, Drosophila, plants and mammals. MicroRNAs have been linked to developmental processes in C. elegans, plants and humans and to cell growth and apoptosis in Drosophila. A major impediment in the study of microRNA function is the lack of quantitative expression profiling methods. To close this technological gap, we have d  ...[more]

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