Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

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Tumor T1 Sectors


ABSTRACT: The following CGH experiments were conducted on four sectors (S1-S4) from a single primary ductal carcinoma tumor (T1). The genomic DNA from each tumor sector was labeled with Cy5 and hybridized to an 85K Bgl2 ROMA Microarray. A normal reference male fibroblast was labeled with Cy3 as a control. Samples were dye-swapped and the experiments were conducted in color-reversal. The value data repesents a log ratio of the mean of two dye-swapped samples

ORGANISM(S): Homo sapiens

SUBMITTER: Nicholas Navin 

PROVIDER: E-GEOD-16598 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

High-resolution nucleosome mapping reveals transcription-dependent promoter packaging.

Weiner Assaf A   Hughes Amanda A   Yassour Moran M   Rando Oliver J OJ   Friedman Nir N  

Genome research 20091021 1


Genome-wide mapping of nucleosomes has revealed a great deal about the relationships between chromatin structure and control of gene expression, and has led to mechanistic hypotheses regarding the rules by which chromatin structure is established. High-throughput sequencing has recently become the technology of choice for chromatin mapping studies, yet analysis of these experiments is still in its infancy. Here, we introduce a pipeline for analyzing deep sequencing maps of chromatin structure an  ...[more]

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