Ontology highlight
ABSTRACT:
ORGANISM(S): Aspergillus fumigatus
SUBMITTER: Scott Tebbutt
PROVIDER: E-GEOD-16637 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Gomez Pol P Hackett Tillie L TL Moore Margo M MM Knight Darryl A DA Tebbutt Scott J SJ
BMC genomics 20100604
<h4>Background</h4>Aspergillus fumigatus (A. fumigatus) is a ubiquitous fungus which reproduces asexually by releasing abundant airborne conidia (spores), which are easily respirable. In allergic and immunocompromised individuals A. fumigatus can cause a wide spectrum of diseases, including allergic bronchopulmonary aspergillosis, aspergilloma and invasive aspergillosis. Previous studies have demonstrated that A. fumigatus conidia are internalized by macrophages and lung epithelial cells; howeve ...[more]