Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

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Transcriptomic analysis of interactions between Aspergillus fumigatus conidiospores and human bronchial epithelial cells


ABSTRACT: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

ORGANISM(S): Aspergillus fumigatus

SUBMITTER: Scott Tebbutt 

PROVIDER: E-GEOD-16637 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Functional genomics of human bronchial epithelial cells directly interacting with conidia of Aspergillus fumigatus.

Gomez Pol P   Hackett Tillie L TL   Moore Margo M MM   Knight Darryl A DA   Tebbutt Scott J SJ  

BMC genomics 20100604


<h4>Background</h4>Aspergillus fumigatus (A. fumigatus) is a ubiquitous fungus which reproduces asexually by releasing abundant airborne conidia (spores), which are easily respirable. In allergic and immunocompromised individuals A. fumigatus can cause a wide spectrum of diseases, including allergic bronchopulmonary aspergillosis, aspergilloma and invasive aspergillosis. Previous studies have demonstrated that A. fumigatus conidia are internalized by macrophages and lung epithelial cells; howeve  ...[more]

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