Regional brain expression maps for microRNAs in rats
Ontology highlight
ABSTRACT:
ORGANISM(S): Rattus norvegicus
SUBMITTER: Mikkel Klausen
PROVIDER: E-GEOD-16725 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
MicroRNAs show mutually exclusive expression patterns in the brain of adult male rats.
Olsen Line L Klausen Mikkel M Helboe Lone L Nielsen Finn Cilius FC Werge Thomas T
PloS one 20091006 10
<h4>Background</h4>The brain is a major site of microRNA (miRNA) gene expression, but the spatial expression patterns of miRNAs within the brain have not yet been fully covered.<h4>Methodology/principal findings</h4>We have characterized the regional expression profiles of miRNAs in five distinct regions of the adult rat brain: amygdala, cerebellum, hippocampus, hypothalamus and substantia nigra. Microarray profiling uncovered 48 miRNAs displaying more than three-fold enrichment between two or m ...[more]
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