Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

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H2O2 treatment of myotubes


ABSTRACT: Study to examine changes in gene expression in C2C12 myotubes at 5 days post-differentiation following treatment with a non-damaging concentration of hydrogen peroxide)

ORGANISM(S): Mus musculus

SUBMITTER: Anne McArdle 

PROVIDER: E-GEOD-1678 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Preconditioning of skeletal muscle against contraction-induced damage: the role of adaptations to oxidants in mice.

McArdle F F   Spiers S S   Aldemir H H   Vasilaki A A   Beaver A A   Iwanejko L L   McArdle A A   Jackson M J MJ  

The Journal of physiology 20040826 Pt 1


Adaptations of skeletal muscle following exercise are accompanied by changes in gene expression, which can result in protection against subsequent potentially damaging exercise. One cellular signal activating these adaptations may be an increased production of reactive oxygen and nitrogen species (ROS). The aim of this study was to examine the effect of a short period of non-damaging contractions on the subsequent susceptibility of muscle to contraction-induced damage and to examine the changes  ...[more]

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