Dataset Information
Pyrococcus furiosus psiRNAs
Ontology highlight
ABSTRACT:
ORGANISM(S): Pyrococcus furiosus
SUBMITTER: Brenton Graveley
PROVIDER: E-GEOD-16968 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
RNA-guided RNA cleavage by a CRISPR RNA-Cas protein complex.
Cell 20091101 5
Compelling evidence indicates that the CRISPR-Cas system protects prokaryotes from viruses and other potential genome invaders. This adaptive prokaryotic immune system arises from the clustered regularly interspaced short palindromic repeats (CRISPRs) found in prokaryotic genomes, which harbor short invader-derived sequences, and the CRISPR-associated (Cas) protein-coding genes. Here, we have identified a CRISPR-Cas effector complex that is comprised of small invader-targeting RNAs from the CRIS ...[more]
