Whole genome expression profile of dsap18 mutant Drosophila melanogaster embryos
Ontology highlight
ABSTRACT:
ORGANISM(S): Drosophila melanogaster
SUBMITTER: Sergi Beltran
PROVIDER: E-GEOD-17066 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Drosophila melanogaster SAP18 protein is required for environmental stress responses.
Costa Elisabet E Beltran Sergi S Espinàs M Lluisa ML
FEBS letters 20101210 2
SAP18, a highly evolutionarily conserved protein, has been proposed to be involved in multiple cellular processes, from gene regulation to mRNA processing. To gain further insight into the role of SAP18, we performed genome-wide expression profiling of dsap18 mutant Drosophila melanogaster embryos and we found that dSAP18 is required for the expression of immune and stress related genes. We show that dSAP18 colocalizes with histone H3 phosphorylation, which has been implicated in the regulation ...[more]
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