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MicroRNA expression profiling of male breast cancer

ABSTRACT: To test the hypothesis that there is a specific miRNA expression signature which characterizes male breast cancers, we performed miRNA microarray analysis in a series of male breast cancers and compared them to cases of male gynecomastia and female breast cancers miRNA microarray analysis was performed in a series of 23 male breast cancers, 5 cases of gynecomastia and 10 female ductal breast carcinomas

ORGANISM(S): Homo sapiens

SUBMITTER: Stefano Volinia

PROVIDER: E-GEOD-17155 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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MicroRNA expression profiling of male breast cancer.

Fassan Matteo M Baffa Raffaele R Palazzo Juan P JP Lloyd Joshua J Crosariol Marco M Liu Chang-Gong CG Volinia Stefano S Alder Hannes H Rugge Massimo M Croce Carlo M CM Rosenberg Anne A

Breast cancer research : BCR 20090810 4

<h4>Introduction</h4>MicroRNAs (miRNAs) are a class of small noncoding RNAs that control gene expression by targeting mRNAs and triggering either translation repression or RNA degradation. Their aberrant expression may be involved in human diseases, including cancer. To test the hypothesis that there is a specific miRNA expression signature which characterizes male breast cancers, we performed miRNA microarray analysis in a series of male breast cancers and compared them with cases of male gynec ...[more]

PMID: 19664288

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