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Human and Mouse Cells Time of Replication (ToR)

ABSTRACT: This SuperSeries is composed of the following subset Series: GSE17229: Mouse Cells Time of Replication (ToR) GSE17235: Human Cells Time of Replication (ToR) Refer to individual Series

ORGANISM(S): Mus musculus

SUBMITTER: Itamar Simon

PROVIDER: E-GEOD-17236 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Comparative analysis of DNA replication timing reveals conserved large-scale chromosomal architecture.

Yaffe Eitan E Farkash-Amar Shlomit S Polten Andreas A Yakhini Zohar Z Tanay Amos A Simon Itamar I

PLoS genetics 20100701 7

Recent evidence suggests that the timing of DNA replication is coordinated across megabase-scale domains in metazoan genomes, yet the importance of this aspect of genome organization is unclear. Here we show that replication timing is remarkably conserved between human and mouse, uncovering large regions that may have been governed by similar replication dynamics since these species have diverged. This conservation is both tissue-specific and independent of the genomic G+C content conservation. ...[more]

PMID: 20617169

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Mouse Cells Time of Replication (ToR)

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2010-05-25 | E-GEOD-17229 | biostudies-arrayexpress

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