Unknown,Transcriptomics,Genomics,Proteomics

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Parasite resistance in the small intestine of sheep


ABSTRACT: This experiment details the gene expression data from the small intestine from a set of parasite resistant and a set of parasite susceptible sheep. Keywords = parasite resistance

ORGANISM(S): Ovis aries

SUBMITTER: Cristina Diez-Tascon 

PROVIDER: E-GEOD-1728 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Microarray analysis of selection lines from outbred populations to identify genes involved with nematode parasite resistance in sheep.

Diez-Tascón Cristina C   Keane Orla M OM   Wilson Theresa T   Zadissa Amonida A   Hyndman Dianne L DL   Baird David B DB   McEwan John C JC   Crawford Allan M AM  

Physiological genomics 20041228 1


Gastrointestinal nematodes infect sheep grazing contaminated pastures. Traditionally, these have been controlled with anthelmintic drenching. The selection of animals resistant to nematodes is an alternative to complete reliance on drugs, but the genetic basis of host resistance is poorly understood. Using a 10,204 bovine cDNA microarray, we have examined differences in gene expression between genetically resistant and susceptible lambs previously field challenged with larval nematodes. Northern  ...[more]

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