Ontology highlight
ABSTRACT:
ORGANISM(S): Saccharomyces cerevisiae
SUBMITTER: Miguel Rodriguez-Gabriel
PROVIDER: E-GEOD-17364 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Matia-González Ana M AM Rodríguez-Gabriel Miguel A MA
Yeast (Chichester, England) 20100824 1
Arsenate is a common toxic metalloid found in drinking water worldwide that causes several human diseases. The biochemical action underlying cellular response to arsenate, however, is not yet completely understood. Here we used Saccharomyces cerevisiae as an eukaryotic model system to identify proteins essential for adaptation to arsenate treatment. Previous studies have demonstrated a function for Hog1 MAPK in modulating the cellular response to arsenite. Our results, however, showed that cells ...[more]