Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Paolo Fardin
PROVIDER: E-GEOD-17714 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Fardin Paolo P Barla Annalisa A Mosci Sofia S Rosasco Lorenzo L Verri Alessandro A Versteeg Rogier R Caron Huib N HN Molenaar Jan J JJ Ora Ingrid I Eva Alessandra A Puppo Maura M Varesio Luigi L
Molecular cancer 20100712
<h4>Background</h4>Hypoxia is a condition of low oxygen tension occurring in the tumor microenvironment and it is related to poor prognosis in human cancer. To examine the relationship between hypoxia and neuroblastoma, we generated and tested an in vitro derived hypoxia gene signature for its ability to predict patients' outcome.<h4>Results</h4>We obtained the gene expression profile of 11 hypoxic neuroblastoma cell lines and we derived a robust 62 probesets signature (NB-hypo) taking advantage ...[more]