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Transcription profiling of human male vastus lateralis muscle samples from healthy and COPD subjects before and after 3 months of training

ABSTRACT: Needle biopsies were obtained from the vastus lateralis muscle of 6 healthy, sedentary, 67 +/- 2.5 year-old males before and after 3 months of training.

ORGANISM(S): Homo sapiens

SUBMITTER: Shlomit Radom-Aizik

PROVIDER: E-GEOD-1786 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Effects of aerobic training on gene expression in skeletal muscle of elderly men.

Radom-Aizik Shlomit S Hayek Shlomo S Shahar Iris I Rechavi Gideon G Kaminski Naftali N Ben-Dov Issahar I

Medicine and science in sports and exercise 20051001 10

<h4>Purpose</h4>To analyze the effect of 3 months of training on global gene expression in skeletal muscle of healthy elderly men in order to better characterize the pathways that differentiate the trained from the sedentary state.<h4>Methods</h4>Needle biopsies were obtained from the vastus lateralis of six healthy, sedentary, 68.0 +/- 2.7-yr-old males, before and after 3 months of training at 80% of maximal capacity, that improved peak O2 uptake by 17.8 +/- 4.0% (P = 0.009). RNA extracted from ...[more]

PMID: 16260967

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