Ontology highlight
ABSTRACT:
ORGANISM(S): Salmonella typhimurium SL1344
SUBMITTER: Arthur Thompson
PROVIDER: E-GEOD-18452 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Lucchini Sacha S McDermott Paul P Thompson Arthur A Hinton Jay C D JC
Molecular microbiology 20091019 5
StpA is a paralogue of the nucleoid-associated protein H-NS that is conserved in a range of enteric bacteria and had no known function in Salmonella Typhimurium. We show that 5% of the Salmonella genome is regulated by StpA, which contrasts with the situation in Escherichia coli where deletion of stpA only had minor effects on gene expression. The StpA-dependent genes of S. Typhimurium are a specific subset of the H-NS regulon that are predominantly under the positive control of sigma(38) (RpoS) ...[more]