Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Yoshimichi Okayama
PROVIDER: E-GEOD-1848 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Kashiwakura Jun-ichi J Yokoi Hidenori H Saito Hirohisa H Okayama Yoshimichi Y
Journal of immunology (Baltimore, Md. : 1950) 20041001 8
Mast cells (MCs) are the primary effector cells in allergic reactions and have also been found to activate T cells and to reside in close physical proximity to T cells. However, the molecular mechanisms involved in the MC-T cell interaction remain unclear. We hypothesized that human tonsillar MCs, which locate in the interfollicular areas, might interact with T cells. Thus, we first established a culture system of human tonsillar MCs and then compared gene expression profiles of tonsillar MCs wi ...[more]