Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Michael Birrer
PROVIDER: E-GEOD-18521 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Mok Samuel C SC Bonome Tomas T Vathipadiekal Vinod V Bell Aaron A Johnson Michael E ME Wong Kwong-kwok KK Park Dong-Choon DC Hao Ke K Yip Daniel K P DK Donninger Howard H Ozbun Laurent L Samimi Goli G Brady John J Randonovich Mike M Pise-Masison Cindy A CA Barrett J Carl JC Wong Wing H WH Welch William R WR Berkowitz Ross S RS Birrer Michael J MJ
Cancer cell 20091201 6
Advanced stage papillary serous tumors of the ovary are responsible for the majority of ovarian cancer deaths, yet the molecular determinants modulating patient survival are poorly characterized. Here, we identify and validate a prognostic gene expression signature correlating with survival in a series of microdissected serous ovarian tumors. Independent evaluation confirmed the association of a prognostic gene microfibril-associated glycoprotein 2 (MAGP2) with poor prognosis, whereas in vitro m ...[more]