Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Mayte Suarez-Farinas
PROVIDER: E-GEOD-18948 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Suárez-Fariñas Mayte M Shah Kejal R KR Haider Asifa S AS Krueger James G JG Lowes Michelle A MA
BMC dermatology 20100212
<h4>Background</h4>Alefacept treatment is highly effective in a select group patients with moderate-to-severe psoriasis, and is an ideal candidate to develop systems to predict who will respond to therapy. A clinical trial of 22 patients with moderate to severe psoriasis treated with alefacept was conducted in 2002-2003, as a mechanism of action study. Patients were classified as responders or non-responders to alefacept based on histological criteria. Results of the original mechanism of action ...[more]