Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

Transcription profiling of human response to carboplatin in chemosensitive and chemoresistant ovarian cancer cells.

ABSTRACT: Use of expression arrays to identify genes from ovarian cancer cells that are associated with carboplatin sensitivity and resistance as defined by ChemoFX assay.

ORGANISM(S): Homo sapiens

SUBMITTER: David Gerard Peters

PROVIDER: E-GEOD-1926 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Genome-wide transcriptional analysis of carboplatin response in chemosensitive and chemoresistant ovarian cancer cells.

Peters David D Freund John J Ochs Robert L RL

Molecular cancer therapeutics 20051001 10

We have recently described an ex vivo chemoresponse assay for determining chemosensitivity in primary cultures of human tumors. In this study, we have extended these experiments in an effort to correlate chemoresponse data with gene expression patterns at the level of transcription. Primary cultures of cells derived from ovarian carcinomas of individual patients (n=6) were characterized using the ChemoFx assay and classified as either carboplatin sensitive (n=3) or resistant (n=3). Three represe ...[more]

PMID: 16227411

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Dataset Information

Transcription profiling of human response to carboplatin in chemosensitive and chemoresistant ovarian cancer cells.

Publications

Genome-wide transcriptional analysis of carboplatin response in chemosensitive and chemoresistant ovarian cancer cells.

Similar Datasets

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