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Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of human fibroblasts grown on TCPS plates, Collagen-GAG 2 D plate and Collagen-GAG 3D mesh

ABSTRACT: All mRNA was isolated after 8 hours of culture time in each of three culture conditions. (1) TCPS Plate, (2) Collagen-GAG 2 dimensional coated plate and (3) collagen-GAG three dimensional mesh.

ORGANISM(S): Homo sapiens

SUBMITTER: Catherine Klapperich

PROVIDER: E-GEOD-1937 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Fibroblast remodeling activity at two- and three-dimensional collagen-glycosaminoglycan interfaces.

Jaworski Justyn J Klapperich Catherine M CM

Biomaterials 20060418 23

Previously we demonstrated that high throughput gene expression experiments can yield novel information about how cells respond to a collagen-glycosaminoglycan (GAG) three-dimensional culture environment. The goal of the current study was to determine which of these differences result from culture in a three-dimensional construct versus those caused simply by the presence of the collagen-GAG biomaterial. To make this distinction, cells were cultured both in collagen-GAG scaffolds fabricated usin ...[more]

PMID: 16620959

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Collagen-GAG Biocompatibility Tests

Project description:All mRNA was isolated after 8 hours of culture time in each of three culture conditions. (1) TCPS Plate, (2) Collagen-GAG 2 dimensional coated plate and (3) collagen-GAG three dimensional mesh. Keywords: ordered

2004-11-09 | GSE1937 | GEO

IMR-90 cells: Collagen Mesh Time Course

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Transcription profiling of human fibroblasts grown in petri dishes vs. attached to a tissue engineering scaffold sampled at 7 timepoints.

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