Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Carlos Arteaga
PROVIDER: E-GEOD-19639 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Miller Todd W TW Hennessy Bryan T BT González-Angulo Ana M AM Fox Emily M EM Mills Gordon B GB Chen Heidi H Higham Catherine C García-Echeverría Carlos C Shyr Yu Y Arteaga Carlos L CL
The Journal of clinical investigation 20100607 7
Many breast cancers exhibit a degree of dependence on estrogen for tumor growth. Although several therapies have been developed to treat individuals with estrogen-dependent breast cancers, some tumors show de novo or acquired resistance, rendering them particularly elusive to current therapeutic strategies. Understanding the mechanisms by which these cancers develop resistance would enable the development of new and effective therapeutics. In order to determine mechanisms of escape from hormone ...[more]