Ontology highlight
ABSTRACT:
ORGANISM(S): Rattus norvegicus
SUBMITTER: Chiara Gerhardinger
PROVIDER: E-GEOD-1979 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Gerhardinger Chiara C Costa Montserrat Biarnés MB Coulombe Mary C MC Toth Ildiko I Hoehn Todd T Grosu Paul P
Investigative ophthalmology & visual science 20050101 1
<h4>Purpose</h4>To characterize the whole spectrum of gene expression changes induced by diabetes in retinal Müller glial cells.<h4>Methods</h4>Müller cells were isolated from the retina of streptozotocin-diabetic and age-matched control rats by gradient centrifugation and immediately processed for RNA isolation. The gene expression profile of Müller cells was studied with the GeneChip Rat Genome oligonucleotide array (Affymetrix, Santa Clara, CA). The upregulation of acute-phase proteins in the ...[more]