Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Markus Bredel
PROVIDER: E-GEOD-1991 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Bredel Markus M Bredel Claudia C Juric Dejan D Harsh Griffith R GR Vogel Hannes H Recht Lawrence D LD Sikic Branimir I BI
Cancer research 20050501 10
High-resolution genome-wide mapping of exact boundaries of chromosomal alterations should facilitate the localization and identification of genes involved in gliomagenesis and may characterize genetic subgroups of glial brain tumors. We have done such mapping using cDNA microarray-based comparative genomic hybridization technology to profile copy number alterations across 42,000 mapped human cDNA clones, in a series of 54 gliomas of varying histogenesis and tumor grade. This gene-by-gene approac ...[more]