Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: William Rehrauer
PROVIDER: E-GEOD-20086 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Oncogene 20100111 12
Breast carcinoma invasion is associated with prominent alterations in stromal fibroblasts. Carcinoma-associated fibroblasts (CAF) support and promote tumorigenesis, whereas normal mammary fibroblasts (NF) are thought to suppress tumor progression. Little is known about the difference in gene expression between CAF and NF or the patient-to-patient variability in gene expression. Paired CAF and NF were isolated from six primary human breast carcinoma specimens. RNA was extracted from low-passage c ...[more]