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Effects of gene scilencing of USP2 on expression profiles of HL60 cells

ABSTRACT: So far, we have found PMA induced USP2b isoform in myeloid leukemia cell lines such as HL60, THP-1, and U937. To explore molecular function of USP2 in the cells, we assess expression profiles of HL60-derivatives continuously expressing shRNA for USP2 and control shRNA. HL60 derivatives continuously expressing shRNA for USP2 and control shRNA were treated with PMA (30nM) for 0, 1, 2, and 3 days. Total RNA was extracted from the cells and subjected to microarray experiments using Human Genome U133 GeneChips.

ORGANISM(S): Homo sapiens

SUBMITTER: Hiroshi Kitamura

PROVIDER: E-GEOD-20476 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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