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Ets-1 over-expression in ovarian cancer cells

ABSTRACT: The transcription factor Ets-1 is over-expressed in a wide variety of cancers, and has been strongly associated with the upregulation of factors involved in metastasis and angiogenesis. In this study, we created an inducible Ets-1 over-expressing ovarian cancer cell line from parental 2008 ovarian cancer cells that do not express detectable levels of Ets-1 protein. This microarray compares the stable over-expressing Ets-1 ovarian cancer cell line (2008-Ets1) to their parental 2008 cells to examine differences in gene expression beyond metastasis and angiogenesis. Two samples were used: 2008 ovarian cancer cells, and 2008-Ets1 ovarian cancer cells which over-express Ets-1. Included in this analysis are three independent replicates for each sample.

ORGANISM(S): Homo sapiens

SUBMITTER: Meghan Verschoor

PROVIDER: E-GEOD-21129 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Ets-1 over-expression in ovarian cancer cells

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