Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

Genome-wide Patterns of Population Structure and Admixture among Hispanic/Latino Populations

ABSTRACT: Hispanic/Latino populations possess a complex genetic structure that reflects recent admixture among and potentially ancient substructure within Native American, European, and West African source populations. Here, we quantify genome-wide patterns of SNP and haplotype variation among 100 individuals with ancestry from Ecuador, Colombia, Puerto Rico, and the Dominican Republic genotyped using Illumina technology. To investigate variations of continental ancestry between different Hispanic/Latino groups (using self-reported country-specific identification of individual, both parents, and all four grandparents) and within them from healthy controls represented in the New York Health Project Biorepository. Genotyped on the Illumina 610-Quad, which is identical to HumanHap550-v3 SNPs plus an additional ~60,000 SNPs for CNV, no CNV data is provided or was analyzed.

ORGANISM(S): Homo sapiens

SUBMITTER: Harry Ostrer

PROVIDER: E-GEOD-21248 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Colloquium paper: genome-wide patterns of population structure and admixture among Hispanic/Latino populations.

Bryc Katarzyna K Velez Christopher C Karafet Tatiana T Moreno-Estrada Andres A Reynolds Andy A Auton Adam A Hammer Michael M Bustamante Carlos D CD Ostrer Harry H

Proceedings of the National Academy of Sciences of the United States of America 20100505

Hispanic/Latino populations possess a complex genetic structure that reflects recent admixture among and potentially ancient substructure within Native American, European, and West African source populations. Here, we quantify genome-wide patterns of SNP and haplotype variation among 100 individuals with ancestry from Ecuador, Colombia, Puerto Rico, and the Dominican Republic genotyped on the Illumina 610-Quad arrays and 112 Mexicans genotyped on Affymetrix 500K platform. Intersecting these data ...[more]

PMID: 20445096

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Dataset Information

Genome-wide Patterns of Population Structure and Admixture among Hispanic/Latino Populations

Publications

Colloquium paper: genome-wide patterns of population structure and admixture among Hispanic/Latino populations.

Similar Datasets

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