Unknown,Transcriptomics,Genomics,Proteomics

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Systems biology of interstitial lung diseases


ABSTRACT: This SuperSeries is composed of the following subset Series: GSE21369: Gene expression profiles of interstitial lung disease (ILD) patients GSE21394: MicroRNA expression profiles of interstitial lung disease (ILD) patients Refer to individual Series

ORGANISM(S): Homo sapiens

SUBMITTER: Ji-Hoon Cho 

PROVIDER: E-GEOD-21411 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Systems biology of interstitial lung diseases: integration of mRNA and microRNA expression changes.

Cho Ji-Hoon JH   Gelinas Richard R   Wang Kai K   Etheridge Alton A   Piper Melissa G MG   Batte Kara K   Dakhallah Duaa D   Price Jennifer J   Bornman Dan D   Zhang Shile S   Marsh Clay C   Galas David D  

BMC medical genomics 20110117


<h4>Background</h4>The molecular pathways involved in the interstitial lung diseases (ILDs) are poorly understood. Systems biology approaches, with global expression data sets, were used to identify perturbed gene networks, to gain some understanding of the underlying mechanisms, and to develop specific hypotheses relevant to these chronic lung diseases.<h4>Methods</h4>Lung tissue samples from patients with different types of ILD were obtained from the Lung Tissue Research Consortium and total c  ...[more]

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