Unknown,Transcriptomics,Genomics,Proteomics

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Expression profiling of Moraxella catarrhalis RH4 during in vitro growth in brain heart infusion (BHI) medium


ABSTRACT: Transcriptome analysis of M. catarrhalis RH4 predicted coding sequences and clustered regularly interspaced short palindromic repeats (CRISPRs) regions. The results described in this study are further discussed in De Vries, S.P.W., van Hijum, S.A.F.T., Schueler, W., Riesbeck, K., Hays, J.P., Hermans, P.W.M., Bootsma, H.J.; Genome analysis of Moraxella catarrhalis strain RH4: a human respiratory tract pathogen; Journal of Bacteriology Total RNA from lag phase (OD620 = 0.2-0.3), exponential phase (OD620 = 1.2-1.4), or stationary phase (OD620 = 2.0-2.2) bacteria grown in triplicate in BHI medium, and hybridized in duplicate on 4x72K custom design Nimblegen arrays

ORGANISM(S): Moraxella catarrhalis RH4

SUBMITTER: Hester Bootsma 

PROVIDER: E-GEOD-21632 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Genome analysis of Moraxella catarrhalis strain BBH18, [corrected] a human respiratory tract pathogen.

de Vries Stefan P W SP   van Hijum Sacha A F T SA   Schueler Wolfgang W   Riesbeck Kristian K   Hays John P JP   Hermans Peter W M PW   Bootsma Hester J HJ  

Journal of bacteriology 20100507 14


Moraxella catarrhalis is an emerging human-restricted respiratory tract pathogen that is a common cause of childhood otitis media and exacerbations of chronic obstructive pulmonary disease in adults. Here, we report the first completely assembled and annotated genome sequence of an isolate of M. catarrhalis, strain RH4, which originally was isolated from blood of an infected patient. The RH4 genome consists of 1,863,286 nucleotides that form 1,886 protein-encoding genes. Comparison of the RH4 ge  ...[more]

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