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Transcription profiling of 22 Pancreatic Cancer Cell Lines

ABSTRACT: We used microarrays to analyze the global expression patterns for 22 commercially available pancreatic cancer cell lines 22 pancreatic cancer cell lines were grown to 80% confluence in DMEM/FBS/PenStrep media and then harvested for total RNA

ORGANISM(S): Homo sapiens

SUBMITTER: Emily Euger 

PROVIDER: E-GEOD-21654 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Glycogene expression alterations associated with pancreatic cancer epithelial-mesenchymal transition in complementary model systems.

Maupin Kevin A KA   Sinha Arkadeep A   Eugster Emily E   Miller Jeremy J   Ross Julianna J   Paulino Vincent V   Keshamouni Venkateshwar G VG   Tran Nhan N   Berens Michael M   Webb Craig C   Haab Brian B BB  

PloS one 20100927 9

<h4>Background</h4>The ability to selectively detect and target cancer cells that have undergone an epithelial-mesenchymal transition (EMT) may lead to improved methods to treat cancers such as pancreatic cancer. The remodeling of cellular glycosylation previously has been associated with cell differentiation and may represent a valuable class of molecular targets for EMT.<h4>Methodology/principal findings</h4>As a first step toward investigating the nature of glycosylation alterations in EMT, w  ...[more]

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