Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Transcriptional profiling of 29 cases of diffuse large B cell lymphoma

ABSTRACT: 29 cases of RCHOP treated DLBCL were profiled for gene expression. Different integrated annalysis were performed, including mirNA differential expression between cases classified according to the COO signature (see later) and correlation tests between gene and miRNA expression. After transcriptional profiling the cases were classified according to the cell of origin based on the classifier proposed by Wright et al (Wright G, Tan B, Rosenwald A, Hurt EH, Wiestner A, Staudt LM. A gene expression-based method to diagnose clinically distinct subgroups of diffuse large B cell lymphoma. Proc Natl Acad Sci U S A 2003;100:9991-6.).

ORGANISM(S): Homo sapiens

SUBMITTER: Santiago Montes-Moreno 

PROVIDER: E-GEOD-21846 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Json Xml
altmetric image

Publications

Diffuse large B-cell lymphoma (DLBCL) prognostication requires additional biologic markers. miRNAs may constitute markers for cancer diagnosis, outcome, or therapy response. In the present study, we analyzed the miRNA expression profile in a retrospective multicenter series of 258 DLBCL patients uniformly treated with chemoimmunotherapy. Findings were correlated with overall survival (OS) and progression-free survival (PFS). miRNA and gene-expression profiles were studied using microarrays in an  ...[more]

Similar Datasets

Transcriptomics miRNA profiling of 29 cases of diffuse large B cell lymphoma
2011-08-01 | E-GEOD-21847 | biostudies-arrayexpress
Transcriptomics miRNA profiling of 36 cases of diffuse large B cell lymphoma
2011-08-01 | E-GEOD-21848 | biostudies-arrayexpress
Transcriptomics Gene and microRNA expression data of diffuse large B cell lymphoma from human diagnostic frozen samples
2011-08-01 | E-GEOD-21849 | biostudies-arrayexpress
Genomics miRNA profiling of 29 cases of diffuse large B cell lymphoma
2011-08-02 | GSE21847 | GEO
Transcriptomics Transcriptional profiling of 29 cases of diffuse large B cell lymphoma
2011-08-02 | GSE21846 | GEO
Transcriptomics Cell-of-Origin Subtyping Diffuse Large B-Cell Lymphoma (DLCBL) by Using a 32-Gene Expression Assay in Formalin-Fixed Paraffin-Embedded Tissues
2020-04-22 | GSE147986 | GEO
Genomics Unravelling the heterogeneous molecular landscape of pediatric post-transplant lymphoproliferative disorders
2023-12-19 | GSE198253 | GEO
Transcriptomics DLBCL cell-of-origin by gene expression in FFPET
2014-01-14 | GSE53786 | GEO
Transcriptomics Expression profiling of GIST: CD133 is associated with KIT exon 11 deletion, gastric location and poor prognosis
2010-06-30 | E-GEOD-14755 | biostudies-arrayexpress
Transcriptomics DLBCL cell-of-origin by gene expression in FFPET
2014-01-14 | E-GEOD-53786 | biostudies-arrayexpress