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The mRNA levels of CD133 positive and CD133 negative cells after radiation exposure

ABSTRACT: The cancer initiating cells (CICs) act as a tumor initiation source. Recent studies have shown that CICs contribute to chemoresistance and radioresistance. The aims of this study were to investigate the relationship of CD133+ liver CICs and radiation resistance and to define a possible mechanism for radioresistance in hepatocellular carcinoma (HCC). Total RNA is obtained from CD133 positive cells and CD133 negative cells at 0, 12 and 24 hours after radiation exposure.

ORGANISM(S): Homo sapiens

SUBMITTER: Taek-Kyun Kim

PROVIDER: E-GEOD-22247 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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The mRNA levels of CD133 positive and CD133 negative cells after radiation exposure

Project description:The cancer initiating cells (CICs) act as a tumor initiation source. Recent studies have shown that CICs contribute to chemoresistance and radioresistance. The aims of this study were to investigate the relationship of CD133+ liver CICs and radiation resistance and to define a possible mechanism for radioresistance in hepatocellular carcinoma (HCC).

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Benign Uncultured CD133+ vs CD133-

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CD133+ and CD133- expression profiles of benign and HRPC cells

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Project description:Gene expression and pathway analysis of sorted CD133 negative and CD133 positive population

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