Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: LIGUO WANG
PROVIDER: E-GEOD-22260 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Kannan Kalpana K Wang Liguo L Wang Jianghua J Ittmann Michael M MM Li Wei W Yen Laising L
Proceedings of the National Academy of Sciences of the United States of America 20110512 22
Transcription-induced chimeric RNAs, possessing sequences from different genes, are expected to increase the proteomic diversity through chimeric proteins or altered regulation. Despite their importance, few studies have focused on chimeric RNAs especially regarding their presence/roles in human cancers. By deep sequencing the transcriptome of 20 human prostate cancer and 10 matched benign prostate tissues, we obtained 1.3 billion sequence reads, which led to the identification of 2,369 chimeric ...[more]