Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Changes in Hepatic Gene Expression upon Oral Administration of Taurine-Conjugated Ursodeoxycholic Acid in ob/ob Mice


ABSTRACT: We examined the effect of oral TUDCA treatment on hepatic steatosis and associated changes in hepatic gene expression in ob/ob mice. We administered TUDCA to ob/ob mice at a dose of 500 mg/kg twice a day by gastric gavage for 3 weeks. Body weight, glucose homeostasis, endoplasmic reticulum (ER) stress, and hepatic gene expression were examined in comparison with control ob/ob mice and normal littermate C57BL/6J mice.

ORGANISM(S): Mus musculus

SUBMITTER: Jae-Seong Yang 

PROVIDER: E-GEOD-22608 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Similar Datasets

2014-06-29 | E-MTAB-2678 | biostudies-arrayexpress
2012-03-29 | E-GEOD-35075 | biostudies-arrayexpress
2021-03-21 | PXD018783 | Pride
2014-03-04 | E-GEOD-49195 | biostudies-arrayexpress
2021-03-21 | PXD024239 | Pride
2021-03-21 | PXD023581 | Pride
2013-09-25 | E-GEOD-46110 | biostudies-arrayexpress
2023-05-15 | E-MTAB-12623 | biostudies-arrayexpress
2013-03-22 | E-GEOD-31952 | biostudies-arrayexpress
2010-10-22 | E-GEOD-24851 | biostudies-arrayexpress