Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Baptiste JANELA
PROVIDER: E-GEOD-23015 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Picard Damien D Janela Baptiste B Descamps Vincent V D'Incan Michel M Courville Philippe P Jacquot Serge S Rogez Sylvie S Mardivirin Laurent L Moins-Teisserenc Hélène H Toubert Antoine A Benichou Jacques J Joly Pascal P Musette Philippe P
Science translational medicine 20100801 46
Drug reaction with eosinophilia and systemic symptoms (DRESS) is a severe, drug-induced reaction that involves both the skin and the viscera. Evidence for reactivation of herpes family viruses has been seen in some DRESS patients. To understand the immunological components of DRESS and their relationship to viral reactivation, we prospectively assessed 40 patients exhibiting DRESS in response to carbamazepine, allopurinol, or sulfamethoxazole. Peripheral blood T lymphocytes from the patients wer ...[more]