Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Garrett Frampton
PROVIDER: E-GEOD-23402 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Guenther Matthew G MG Frampton Garrett M GM Soldner Frank F Hockemeyer Dirk D Mitalipova Maya M Jaenisch Rudolf R Young Richard A RA
Cell stem cell 20100801 2
Knowledge of both the global chromatin structure and the gene expression programs of human embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) should provide a robust means to assess whether the genomes of these cells have similar pluripotent states. Recent studies have suggested that ESCs and iPSCs represent different pluripotent states with substantially different gene expression profiles. We describe here a comparison of global chromatin structure and gene expression data f ...[more]