Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Stephanie Ma
PROVIDER: E-GEOD-23450 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Hepatology (Baltimore, Md.) 20120113 3
<h4>Unlabelled</h4>A novel theory in the field of tumor biology postulates that cancer growth is driven by a population of stem-like cells, called tumor-initiating cells (TICs). We previously identified a TIC population derived from hepatocellular carcinoma (HCC) that is characterized by membrane expression of CD133. Here, we describe a novel mechanism by which these cells mediate tumor growth and angiogenesis by systematic comparison of the gene expression profiles between sorted CD133 liver su ...[more]