Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Pascal FINETTI
PROVIDER: E-GEOD-23720 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Bekhouche Ismahane I Finetti Pascal P Adelaïde José J Ferrari Anthony A Tarpin Carole C Charafe-Jauffret Emmanuelle E Charpin Colette C Houvenaeghel Gilles G Jacquemier Jocelyne J Bidaut Ghislain G Birnbaum Daniel D Viens Patrice P Chaffanet Max M Bertucci François F
PloS one 20110209 2
<h4>Background</h4>Inflammatory breast cancer (IBC) is an aggressive form of BC poorly defined at the molecular level. We compared the molecular portraits of 63 IBC and 134 non-IBC (nIBC) clinical samples.<h4>Methodology/findings</h4>Genomic imbalances of 49 IBCs and 124 nIBCs were determined using high-resolution array-comparative genomic hybridization, and mRNA expression profiles of 197 samples using whole-genome microarrays. Genomic profiles of IBCs were as heterogeneous as those of nIBCs, a ...[more]