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Non-M1 covRS-intact and -mutant GAS vs M1 controls

ABSTRACT: Microarray was performed on RNA extracted from mid-logarithmic phase in vitro grown non-M1 Streptococcus pyogenes isolates, with either intact or mutant covRS operons. These isolates were compared with corresponding M1 covRS intact and mutant forms to link the expression prolfiles of these non-M1 isolates with invasive pathogenesis. A dye-swapped cyclic design was used in this study in order that each strain could be compared across all samples in silico. For each strain treated, 2 biological replicates were each analysed in dye-swapped technical replicates, giving a total of n=4 peplicates for each strain.

ORGANISM(S): Streptococcus pyogenes

SUBMITTER: Peter Maamary

PROVIDER: E-GEOD-23825 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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non-M1 covRS-intact and -mutant GAS vs M1 controls

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