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NF-kB suppresses genomic instability in non-Hodgkin lymphomas

ABSTRACT: Oci-Ly3 and Daudi cell lines expressing p100-, p105- and luciferase-siRNA were used to identify genes that are regulated by p100 or p105 in each cell line. p100- (n=3) and p105- (n=3) expressing cells were compared to Luciferase siRNA, using linear models and signficant genes were identified using FDR of 0.001. Then the results for Daudi and OCI-LY3 cell lines were compared and only genes commonly regulated in both cell lines by p100 or p105 were selected for furhter studies.

ORGANISM(S): Homo sapiens

SUBMITTER: Xiangxue Guo

PROVIDER: E-GEOD-24020 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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NF-kB suppresses genomic instability in non-Hodgkin lymphomas

Project description:Oci-Ly3 and Daudi cell lines expressing p100-, p105- and luciferase-siRNA were used to identify genes that are regulated by p100 or p105 in each cell line.

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