Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Thomas Wu
PROVIDER: E-GEOD-24283 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Nacu Serban S Yuan Wenlin W Kan Zhengyan Z Bhatt Deepali D Rivers Celina Sanchez CS Stinson Jeremy J Peters Brock A BA Modrusan Zora Z Jung Kenneth K Seshagiri Somasekar S Wu Thomas D TD
BMC medical genomics 20110124
<h4>Background</h4>Readthrough fusions across adjacent genes in the genome, or transcription-induced chimeras (TICs), have been estimated using expressed sequence tag (EST) libraries to involve 4-6% of all genes. Deep transcriptional sequencing (RNA-Seq) now makes it possible to study the occurrence and expression levels of TICs in individual samples across the genome.<h4>Methods</h4>We performed single-end RNA-Seq on three human prostate adenocarcinoma samples and their corresponding normal tis ...[more]