Ontology highlight
ABSTRACT:
ORGANISM(S): Caenorhabditis elegans
SUBMITTER: Everett Zhou
PROVIDER: E-GEOD-24318 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Ikegami Kohta K Egelhofer Thea A TA Strome Susan S Lieb Jason D JD
Genome biology 20101223 12
<h4>Background</h4>Although Caenorhabditis elegans was the first multicellular organism with a completely sequenced genome, how this genome is arranged within the nucleus is not known.<h4>Results</h4>We determined the genomic regions associated with the nuclear transmembrane protein LEM-2 in mixed-stage C. elegans embryos via chromatin immunoprecipitation. Large regions of several megabases on the arms of each autosome were associated with LEM-2. The center of each autosome was mostly free of su ...[more]