Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Johannes Bjørnstad
PROVIDER: E-GEOD-24454 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Bjørnstad Johannes Lagethon JL Sjaastad Ivar I Nygård Ståle S Hasic Almira A Ahmed Mohammad Shakil MS Attramadal Håvard H Finsen Alexandra Vanessa AV Christensen Geir G Tønnessen Theis T
European heart journal 20100605 2
<h4>Aims</h4>Aortic stenosis induces pressure overload and myocardial remodelling with concentric hypertrophy and alterations in extracellular matrix (ECM). Aortic valve replacement leads to reverse remodelling, a process of which knowledge is scarce. The aims of the present study were to examine alterations in myocardial gene expression and subsequently identify molecular alterations important for the early phase of reverse remodelling.<h4>Methods and results</h4>After 4 weeks of ascending aort ...[more]