Dataset Information
Transcriptomic alterations induced by AT-EAE in mouse spinal cord
Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Eliana Scemes
PROVIDER: E-GEOD-2446 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Alteration of transcriptomic networks in adoptive-transfer experimental autoimmune encephalomyelitis.
Frontiers in integrative neuroscience 20071230
Adoptive transfer experimental autoimmune encephalomyelitis (AT-EAE) is an inflammatory demyelination that recapitulates in mouse spinal cord (SC) the human multiple sclerosis disease. We now analyze previously reported cDNA array data from age-matched young female adult control and passively myelin antigen-sensitized EAE mice with regard to organizational principles of the SC transcriptome in autoimmune demyelination. Although AT-EAE had a large impact on immune response genes, broader function ...[more]
