Unknown,Transcriptomics,Genomics,Proteomics

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Drosophila brain gene expression with age: mRNA profiling


ABSTRACT: Gene expression profile in fly brains during development

ORGANISM(S): Drosophila melanogaster

SUBMITTER: Bonini Nancy 

PROVIDER: E-GEOD-25007 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

The microRNA miR-34 modulates ageing and neurodegeneration in Drosophila.

Liu Nan N   Landreh Michael M   Cao Kajia K   Abe Masashi M   Hendriks Gert-Jan GJ   Kennerdell Jason R JR   Zhu Yongqing Y   Wang Li-San LS   Bonini Nancy M NM  

Nature 20120215 7386


Human neurodegenerative diseases have the temporal hallmark of afflicting the elderly population. Ageing is one of the most prominent factors to influence disease onset and progression, yet little is known about the molecular pathways that connect these processes. To understand this connection it is necessary to identify the pathways that functionally integrate ageing, chronic maintenance of the brain and modulation  ...[more]

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