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Human Fetal and Adult Peripheral Naïve CD4+ T cells and CD4+CD25+ Treg cells

ABSTRACT: We compared differences in fetal and adult T cells by performing whole genome profiling on sort-purified T cells (naïve CD4+ and Treg cells) from human fetal specimens (18-22 gestational weeks) and adult specimens (age 25-40 years old). Fetal and Adult Naïve CD4+ T cells phenotype: CD3+CD4+CD45RA+CCR7+CD27+, Fetal and Adult CD4+CD25+ Treg phenotype: CD3+CD4+CD25bright Four different groups were analyzed: Fetal Naïve CD4+ T cells, Adult Naïve CD4+ T cells, Fetal Treg cells, Adult Treg cells. For each group three independent donors were analyzed.

ORGANISM(S): Homo sapiens

SUBMITTER: Jeff Mold

PROVIDER: E-GEOD-25087 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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