Unknown,Transcriptomics,Genomics,Proteomics

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Establishment and Comparative Characterization of Novel Non-Small Cell Lung Cancer Cell Lines and Their Corresponding Tumor Tissue

ABSTRACT: Cell lines play an important role for studying tumor biology and novel therapeutic agents. We demonstrated that cell lines represent a useful and reliable in vitro system for studying basic mechanisms in lung cancer. Moreover, we presented 3 novel, comprehensively characterized SCC cell lines. Establishment and Comparative Characterization of Three Non-Small Cell Lung Cancer Cell Lines and Their Corresponding Tumor Tissue

ORGANISM(S): Homo sapiens

SUBMITTER: Ruprecht Kuner

PROVIDER: E-GEOD-25251 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Establishment and comparative characterization of novel squamous cell non-small cell lung cancer cell lines and their corresponding tumor tissue.

Gottschling Sandra S Jauch Anna A Kuner Ruprecht R Herpel Esther E Mueller-Decker Karin K Schnabel Philipp A PA Xu Elizabeth C EC Muley Thomas T Sültmann Holger H Bender Christian C Granzow Martin M Efferth Thomas T Efferth Thomas T Hoffmann Hans H Dienemann Hendrik H Herth Felix J F FJ Meister Michael M

Lung cancer (Amsterdam, Netherlands) 20120101 1

<h4>Background</h4>Cell lines play an important role for studying tumor biology and novel therapeutic agents. Particularly in pulmonary squamous cell carcinoma (SCC) the availability of cell lines is limited and knowledge about their representativeness for corresponding tumor tissue is scanty.<h4>Materials and methods</h4>We established three novel SCC cell lines from fresh tumor tissue of 28 donors, including 8 SCC. Two cell lines were derived from different localizations of the same donor, i.e ...[more]

PMID: 21684623

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Dataset Information

Establishment and Comparative Characterization of Novel Non-Small Cell Lung Cancer Cell Lines and Their Corresponding Tumor Tissue

Publications

Establishment and comparative characterization of novel squamous cell non-small cell lung cancer cell lines and their corresponding tumor tissue.

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