Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Ricardo Verdugo
PROVIDER: E-GEOD-25322 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Leduc Magalie S MS Hageman Rachael S RS Verdugo Ricardo A RA Tsaih Shirng-Wern SW Walsh Kenneth K Churchill Gary A GA Paigen Beverly B
Journal of lipid research 20110526 9
To identify genetic loci influencing lipid levels, we performed quantitative trait loci (QTL) analysis between inbred mouse strains MRL/MpJ and SM/J, measuring triglyceride levels at 8 weeks of age in F2 mice fed a chow diet. We identified one significant QTL on chromosome (Chr) 15 and three suggestive QTL on Chrs 2, 7, and 17. We also carried out microarray analysis on the livers of parental strains of 282 F2 mice and used these data to find cis-regulated expression QTL. We then narrowed the li ...[more]